Basic Information
VIS ID
TVIS44027776
Fusion event
HTLV-1-STAU1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
47797288/49180751 (Hg38)
End
47797288/49180751 (Hg38)
Orient
-
Location type
Intronic
Target gene
STAU1
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-27a-3p ; hsa-mir-16-5p ; hsa-mir-877-5p ; hsa-mir-30e-5p ; hsa-mir-5011-5p ; hsa-mir-218-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-222-5p ; hsa-mir-190a-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-1290 ; hsa-mir-16-1-3p ; hsa-mir-4781-3p ; hsa-mir-218-2-3p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-9-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/2013693; hsa-mir-1-1/Downstream/683108;
Nearest TSS
ENST00000382410/Upstream/6488; ENST00000462328/Downstream/7616;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/133839, chr20-CpG: 83/Downstream/7065
Upstream sequence
GCAGTAATTTAGGAGCTGGCCTCCTTTAACACAAAGGTTAATAAGACAGCCCCTCCCCACACACAAACCTGTGGATCAGCTTTAAGTTTTAGCTTAATTT
Downstream sequence
GACATAACAAATAAAAGTAAACTGGAAAGCTATTTCAAGGGTCCATCTAAAAGACTATTACTTAACCAGACTTTCTTTCAAATTGATCTAGGGTTCTAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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