Basic Information
VIS ID
TVIS44027777
Fusion event
HTLV-1-RNF114 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
48567218/49950681 (Hg38)
End
48567218/49950681 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNF114
miRNAs that regulate target gene
hsa-mir-7-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/86728; hsa-mir-1-1/Downstream/635105;
Nearest TSS
ENST00000382410/Upstream/6750; ENST00000244050/Downstream/32318;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/13684, chr20-CpG: 85/Downstream/31741
Upstream sequence
ctgggacaggaggatctcttgagcccaagagacggaggttgcagcaagctgagatcatgccactgcactccagcctgggcaacagaatgagaccctgtct
Downstream sequence
caaaaaaaaaaaaaaaaaacaaaaCACACACACACAACAACAATTTGGACTTGGGAGGCTCAATCTCGCATGTCCATGGGGACCATAATTGAAATGATCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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