Basic Information
VIS ID
TVIS44027809
Fusion event
HTLV-1-PRPF6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62651632/64020279 (Hg38)
End
62651632/64020279 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRPF6
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-7977 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-4798-3p ; hsa-mir-6750-3p ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-1/Upstream/77553; hsa-mir-6813/Downstream/56676;
Nearest TSS
ENST00000382410/Upstream/39144; ENST00000444463/Downstream/14065;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/38845, chr20-CpG: 28/Downstream/9329
Upstream sequence
ccgaggtgggtggatcacttgaggtcaggagttcgagaccagcctggccaacatggtgaaacctcgtctctactaaaaatacagaaattagctgggtgtg
Downstream sequence
gtggcaggcgcttgtaatcccagctacttgggaggctgaggcaggagaactgcttgaacctgggaggtggaggtttcagggagctgagatcgcgccactg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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