Basic Information
VIS ID
TVIS44027883
Fusion event
HTLV-1-TUBA8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
18606046/18123279 (Hg38)
End
18606046/18123279 (Hg38)
Orient
-
Location type
Intronic
Target gene
TUBA8
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-3198-1/Upstream/142318; hsa-let-7a-3/Downstream/1840474;
Nearest TSS
ENST00000624155/Upstream/2172; ENST00000608634/Downstream/3428;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/11848, chr22-CpG: 32/Downstream/26690
Upstream sequence
AAACCTGGAGGAGTCAAGGTGGAAGGGAGGAGAGGCAATTGGCGTTGGTGTTCGATGAGCTTtttttttgtttttttgtttgtttgtttttttgagacgg
Downstream sequence
agtctcgctcggtcgcccaggctggagtgcagtggcgtaatctcggctcactgcaagctccgcctcccgggttcaagccattctcctgcctcagcctccc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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