Basic Information
VIS ID
TVIS44027887
Fusion event
HTLV-1-UFD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19437552/19450029 (Hg38)
End
19437552/19450029 (Hg38)
Orient
+
Location type
UTR3
Target gene
UFD1
miRNAs that regulate target gene
hsa-mir-5584-3p ; hsa-mir-2681-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-5006-3p ; hsa-mir-2909 ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-1296-5p ; hsa-mir-6832-3p ; hsa-mir-3160-5p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-204-5p ; hsa-mir-211-5p
Nearest miRNA
hsa-mir-3198-1/Upstream/1469068; hsa-let-7a-3/Downstream/513724;
Nearest TSS
ENST00000624155/Upstream/1797; ENST00000607934/Downstream/4150;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/1996, chr22-CpG: 44/Downstream/29851
Upstream sequence
AAATTAAAATTGGGAGTTGGGGAGTAGGGAAGAAGGAGAGGAACATCTCTTTAGCATTTGTTCATTCTAACATTCACATGTTTGCTTCTCCATGGAGTTG
Downstream sequence
TTTCACTATGAACAGGTTCACTAAGGAGCCAGTTATGTCCATATGAAATGAGAATAAAAGTGCAAACTCATTCAGATCAGGTTCTTCTGAGTGGTGTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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