Basic Information
VIS ID
TVIS44027905
Fusion event
HTLV-1-NEFH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
29881752/29485763 (Hg38)
End
29881752/29485763 (Hg38)
Orient
+
Location type
Exonic
Target gene
NEFH
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-106b-5p ; hsa-mir-142-3p
Nearest miRNA
hsa-mir-1286/Upstream/1025815; hsa-let-7a-3/Downstream/521286;
Nearest TSS
ENST00000624155/Upstream/4650; ENST00000403999/Downstream/25679;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/4510, chr22-CpG: 30/Downstream/67726
Upstream sequence
TCTGGTACTGAGGGCCAGACACTGGCTGGCATGTGATGTGTGTCACCTCTCCTTCCCAGGAAGCCATTCAGCAGCTGGACGCTGAGCTGAGGAACACCAA
Downstream sequence
GTGGGAGATGGCCGCCCAGCTGCGAGAATACCAGGACCTGCTCAATGTCAAGATGGCTCTGGATATAGAGATAGCCGCTTACAGGTGAGACGCACAGGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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