Basic Information
VIS ID
TVIS44027910
Fusion event
HTLV-1-SFI1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
32014384/31618398 (Hg38)
End
32014384/31618398 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA22B
Target gene
SFI1
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-1286/Upstream/458279; hsa-let-7a-3/Downstream/3069;
Nearest TSS
ENST00000624155/Upstream/4012; ENST00000469969/Downstream/7388;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/121287, chr22-CpG: 53/Downstream/11913
Upstream sequence
CCTCCATGGCCCCAGGTGGAAATGCAGATCCAGCTGCTGGCAGAGGAGCTCCAGGCTCAGCGCCAGCCCATTGGCGCCTGCGTTGCCCGCATCCAGGCCC
Downstream sequence
TGCGGCAGGCCCTGTGCTAGCGTGTTCGCACCAGGAACGCAGGTGCTGGGCTGTCGGGGAGGCCTCAGGCCACCTCCAGGAACAGAACACAGTTTTAAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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