Basic Information
VIS ID
TVIS44027914
Fusion event
HTLV-1-SYN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
33399994/33004009 (Hg38)
End
33399994/33004009 (Hg38)
Orient
+
Location type
Intronic
Target gene
SYN3
miRNAs that regulate target gene
hsa-mir-4792 ; hsa-mir-6807-5p ; hsa-mir-186-3p
Nearest miRNA
hsa-mir-1286/Upstream/1382478; hsa-let-7a-3/Downstream/432573;
Nearest TSS
ENST00000624155/Upstream/56430; ENST00000452505/Downstream/10520;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/201728, chr22-CpG: 75/Downstream/53897
Upstream sequence
tatcaggacttggtgcctgtgtcgcagccacttcagctgtggctaaaagagaccaaggtacagctgaggctgttgcttcagagggtgcaagccccaagcc
Downstream sequence
ttggcaccttccacatggtgctggccctgcggatgcacagaagtattcaggtttgggaacctctgcctagatttcagaggatgtatggaaacacttgggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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