Basic Information
VIS ID
TVIS44027918
Fusion event
HTLV-1-APOL3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36537354/36141306 (Hg38)
End
36537354/36141306 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA22A
Target gene
APOL3
Nearest miRNA
hsa-mir-1286/Upstream/804507; hsa-let-7a-3/Downstream/145541;
Nearest TSS
ENST00000624155/Upstream/50158; ENST00000475519/Downstream/7820;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/74943, chr22-CpG: 24/Downstream/181099
Upstream sequence
GTATGGCATGGATTCAGACGCTGATAGATCTGAGTGAGCTCCATTAGATTCTCCTCCAGCTCCTGAGCCTGCCGCCTCAGCTCCTCAGCAGATGCAGACT
Downstream sequence
TTGCCCCCTCATGCAAGTGCTTTGACTCGTATACAAGGTTGACCACATCCAGTGCAAGGAAGATGCCTGAAGTGGTCGCACTCAGGATCCGGGCTCCTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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