Basic Information
VIS ID
TVIS44027919
Fusion event
HTLV-1-TST integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
37410764/37014723 (Hg38)
End
37410764/37014723 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
TST
miRNAs that regulate target gene
hsa-mir-548b-3p ; hsa-let-7d-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-1286/Upstream/727816; hsa-let-7a-3/Downstream/829549;
Nearest TSS
ENST00000624155/Upstream/6882; ENST00000628507/Downstream/4744;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/158056, chr22-CpG: 154/Downstream/3555
Upstream sequence
ggctcagagaggtgatgtcgcttgcctcaggacacacagcaaaggtaagtctgattggtctgcccccaacgcctgtgttctttGACCACCCTGAGCCTCC
Downstream sequence
CTGGAAAAGGAGACTGAGGCTGGGGAATGGATGAGATGACCTCTTGTACTCAACTACTAGAGTTAACATCCCTCAGGCCACTGGTAGGTGTGGATTTTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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