Basic Information
VIS ID
TVIS44027920
Fusion event
HTLV-1-C1QTNF6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
37581398/37185358 (Hg38)
End
37581398/37185358 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA22A
Target gene
C1QTNF6
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-760 ; hsa-mir-4743-5p ; hsa-mir-765 ; hsa-mir-4721 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-3065-3p ; hsa-mir-4733-3p ; hsa-mir-5088-5p ; hsa-mir-4779 ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-1911-3p ; hsa-mir-3714 ; hsa-mir-8055 ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-342-3p ; hsa-mir-338-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-1228-3p ; hsa-mir-3622a-5p ; hsa-mir-3162-5p ; hsa-mir-566 ; hsa-mir-6720-3p ; hsa-mir-4691-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6760-5p
Nearest miRNA
hsa-mir-1286/Upstream/898451; hsa-let-7a-3/Downstream/658914;
Nearest TSS
ENST00000624155/Upstream/10304; ENST00000467664/Downstream/590;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/2738, chr22-CpG: 92/Downstream/13267
Upstream sequence
AGGGCGTGGGGGCGGCCGGAGGAAGAGGCTGAGGATACATGGGCAGGATCCAGGGGGTCCTCAGAGTCACAGCACCGTTGGCAGCCGCTGGCCACAGCTC
Downstream sequence
TGTCAAAGGTGAGCTCCACCATAGGGATCTCACACATCAGGAGAAAGAGCAGGAGCGCTGCCCAGACGGGACCCAGGGCGGCTGTCCCCATGGTGACCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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