Basic Information
VIS ID
TVIS44027937
Fusion event
HTLV-1-RIBC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
45818224/45422344 (Hg38)
End
45818224/45422344 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA22A
Target gene
RIBC2
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1249/Upstream/221325; hsa-let-7a-3/Downstream/338180;
Nearest TSS
ENST00000624155/Upstream/4337; ENST00000450975/Downstream/26399;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/8272, chr22-CpG: 103/Downstream/80070
Upstream sequence
GCTCCTGTGGCCAGGTCGATCTGATTGCTTCTTGCCTCCTTTCAGAGGCCCTCTACACAGAGACAAGGCTGCAGTTTGACGAGACAGCCAAGCACCTCCA
Downstream sequence
GAAGCTGGAAAGCACCACCAGAAAGGCAGTTTGTGCATCTGTGAAAGACTTCAACAAGAGCCAGGTATAGGTACTCCGCGACCTCGGGCTCGACGACTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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