Basic Information
VIS ID
TVIS44027944
Fusion event
HTLV-1-TAFA5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
48994375/48598563 (Hg38)
End
48994375/48598563 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
TAFA5
Nearest miRNA
hsa-let-7a-3/Upstream/324148; hsa-mir-12114/Downstream/181732;
Nearest TSS
ENST00000624155/Upstream/22110; ENST00000406880/Downstream/94684;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/16992, chr22-CpG: 47/Downstream/24542
Upstream sequence
ACAGGAAGGGACGTCTCCTCCTGGTGCCACCTCCTGGGAGAGTGGCCATTTCGTGGGCCCAGCAGTGGCTGCATCTTAGGCAGTTGTGTGAGATGACCTC
Downstream sequence
CATGTAGGCTGCCATGGTGTCACCGGCTGACCTGGTTTCACTCacacttctgacaccaaatgtgtcagtttttcacaccaacaagttctccaactttcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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