Basic Information
VIS ID
TVIS44027948
Fusion event
HTLV-1-IL17REL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50451073/50012644 (Hg38)
End
50451073/50012644 (Hg38)
Orient
+
Location type
Intronic
Target gene
IL17REL
miRNAs that regulate target gene
hsa-mir-4478 ; hsa-mir-4303 ; hsa-mir-4302 ; hsa-mir-3180-5p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-6846-3p ; hsa-mir-6787-3p ; hsa-mir-6747-3p ; hsa-mir-6752-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-1207-3p ; hsa-mir-181a-2-3p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-6776-5p ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-140-3p ; hsa-mir-4653-5p ; hsa-mir-3921
Nearest miRNA
hsa-let-7a-3/Upstream/49705; hsa-mir-12114/Downstream/394798;
Nearest TSS
ENST00000624155/Upstream/3952; ENST00000475190/Downstream/15;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/1552, chr22-CpG: 119/Downstream/1983
Nearby gene
IL17REL(-18) ;
Upstream sequence
CTGAGAACAGGAGAGGCCACATTCTGTAATCCGGGGGATGGCCAGGCTCTGGAAAGTGCCCCAGGTCAGGCCCAAGAACGCGAGTGCTTGCCCAGCCAGC
Downstream sequence
ATCTGGCTGTGCAGTGAGAGCTCCCACTGGTAAGCGTGGATGTGAGTGGGGCAAGTTTGCAGGATGCCCTGTGGCAGCGGCTCCAGGCTGACCCTGCAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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