Basic Information
VIS ID
TVIS44027967
Fusion event
HTLV-1-HTR2C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37/hg19
Start
113867440/114632979 (Hg38)
End
113867440/114632979 (Hg38)
Orient
-
Location type
Intronic
Target gene
HTR2C
miRNAs that regulate target gene
hsa-mir-22-3p
Nearest miRNA
hsa-let-7f-2/Upstream/1852191; hsa-mir-105-1/Downstream/6456;
Nearest TSS
ENST00000429181/Upstream/48897; ENST00000424776/Downstream/384665;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/47999, chrX-CpG: 263/Downstream/556364
Upstream sequence
GTGACCTAATAACCTTGCAAATGAATGTCTATAATGATAGTTTTATTATTTTCTCTTTATTATTTTAACACAGAATGAATGCTATTTCAATATATCTTCA
Downstream sequence
TCCCTTACCCATAAACACAAATATCCCACTGATAATAAGATGTGAGAAGGAAGTCTTTTAAATTGATTTTTAAAACTTAATTTCTTCAAATAATATAGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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