Basic Information
VIS ID
TVIS44027986
Fusion event
HTLV-1-SMARCA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
128593674/129459697 (Hg38)
End
128593674/129459697 (Hg38)
Orient
-
Location type
Intronic
Target gene
SMARCA1
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-9-5p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-let-7f-2/Upstream/8088644; hsa-mir-105-1/Downstream/4709681;
Nearest TSS
ENST00000429181/Upstream/859229; ENST00000486673/Downstream/63549;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2878359, chrX-CpG: 50/Downstream/63177
Upstream sequence
GCTATTCAAGCTTATGAATAAATAAAAGCTGCAGGGATGATAGCCAAATAAAGTCTAACCTTAGAAAAAGGTAGATTAAAGGAAAAGTAAAATGAACTCC
Downstream sequence
AACCCACTGGCATAATTTGCTCGCATTCTATCCAAATCTGGTCCAACTGTAGGAGTCTATGGGATAGAAGCAAACTTAAATACAACAGTTCTATGCCCAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate