Basic Information
VIS ID
TVIS44027995
Fusion event
HTLV-1-ADGRG4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135400867/136318708 (Hg38)
End
135400867/136318708 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADGRG4
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7f-2/Upstream/1771997; hsa-mir-105-1/Downstream/232170;
Nearest TSS
ENST00000429181/Upstream/12687; ENST00000370648/Downstream/169179;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/18205, chrX-CpG: 138/Downstream/178134
Upstream sequence
gagatttatgatgagtttttcctaacacggaaaacacttatgctatgagtgagaaaagcaggggacccaattttccttacaatatgatctcagcctcaca
Downstream sequence
aaaacaagcaaagcctgtgcacagaaaaaaactgaggaaatataccaaaatgttaatggtgattatctctgagtggtgggactctctggctggctttgtt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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