Basic Information
VIS ID
TVIS44028009
Fusion event
HTLV-1-ACE2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
15611076/15592953 (Hg38)
End
15611076/15592953 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACE2
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-3690-1/Upstream/2002607; hsa-let-7f-2/Downstream/1034059;
Nearest TSS
ENST00000429181/Upstream/26244; ENST00000421585/Downstream/8061;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/99391, chrX-CpG: 35/Downstream/53665
Upstream sequence
gagaagggaagataagagctgtgtcttggagaagaagtaggcactggtcatgtagagaagggaggtagagggaagagtctaaaagatggaaggaggttgg
Downstream sequence
aaaagacaaggcattctcaggggacagtgagatgttgaatgaaactggagcaatggtgttcattaggggaaatgaaagacatgagaatggagagacaagc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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