Basic Information
VIS ID
TVIS44028069
Fusion event
HTLV-1-PUDP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
7018811/7100770 (Hg38)
End
7018811/7100770 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRAXB
Target gene
PUDP
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-98-5p ; hsa-mir-346 ; hsa-mir-106a-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-3690-1/Upstream/716807; hsa-let-7f-2/Downstream/47090;
Nearest TSS
ENST00000429181/Upstream/379226; ENST00000217961/Downstream/47355;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/872905, chrX-CpG: 117/Downstream/46882
Upstream sequence
AGGGGAATTCAGGTTTGGCGCAGATAAAAGAGGAGATGGGAGGAGTGCAAAATGAATGGAAACTAGGTCTCCAAGAATGTTCTTTCAGGACAGAAGAGCT
Downstream sequence
ATTTTATCTTCATTTTTGTGACTGGTATAATATTGAGCAGAAACCCTAAGGAAGAACACATTTCTGGATTGGAATTAGGCACGGCCTGTCTTTCTGCTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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