Basic Information
VIS ID
TVIS44028088
Fusion event
HTLV-1-PCDH11X integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
91507304/92252305 (Hg38)
End
91507304/92252305 (Hg38)
Orient
-
Location type
Intronic
Target gene
PCDH11X
miRNAs that regulate target gene
hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-376a-2-5p ; hsa-mir-3935 ; hsa-mir-2115-3p ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-432-3p ; hsa-mir-4775 ; hsa-mir-324-5p ; hsa-mir-1306-5p ; hsa-mir-590-3p
Nearest miRNA
hsa-let-7f-2/Upstream/6348598; hsa-mir-105-1/Downstream/2810836;
Nearest TSS
ENST00000429181/Upstream/416800; ENST00000332647/Downstream/1421263;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/470035, chrX-CpG: 20/Downstream/1421242
Upstream sequence
GTTATATTTATTTAAAAGAAGTAAAAATTAAGTTGGCTTAAAGTTGTAATATTTTTCCTCAGTCATAGGACCTATGTATTTAATTTTCAAGTACAGATTG
Downstream sequence
GAAGAAGGTATTCCACATGGAATACCTGCATTAGCAACCTGACTTCACAAGCTTCTAGTTTGTCATGTTacacacacacacacacacacacacgcaTGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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