Basic Information
VIS ID
TVIS44028104
Fusion event
HTLV-1-STK26 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q26.2
Reference genome
NCBI36/hg18
Start
131001457/132039748 (Hg38)
End
131001457/132039748 (Hg38)
Orient
-
Location type
Intronic
Target gene
STK26
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-4323 ; hsa-mir-4724-5p ; hsa-mir-5000-5p ; hsa-mir-589-3p ; hsa-mir-606 ; hsa-mir-6856-3p
Nearest miRNA
hsa-let-7f-2/Upstream/10668695; hsa-mir-105-1/Downstream/2129630;
Nearest TSS
ENST00000429181/Upstream/16140; ENST00000421483/Downstream/54515;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/16001, chrX-CpG: 103/Downstream/177755
Upstream sequence
CAATGAATGTGTAATTATGCTTTTACTGTGTGTATTTAATTTTCTGCTAAGAGGTAGTAAGGCTATAATATTTGGCTTATGCTTTGGACAAAAGGAAAGT
Downstream sequence
TCTTTGAAATTTTGAATTTTTAGGTTCTCCCTGGCAAATATTTTGATTCCTTGTATTTTTGGAAAATAATAATCATCTACCATCTTCCAGTAGTGCTTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate