Basic Information
VIS ID
TVIS44028120
Fusion event
HTLV-1-CDH2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
23998538/28164576 (Hg38)
End
23998538/28164576 (Hg38)
Orient
+
Location type
Intronic
Target gene
CDH2
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-194-5p ; hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-27b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-199a-5p ; hsa-mir-412-3p ; hsa-mir-411-5p ; hsa-mir-216b-3p ; hsa-mir-1244 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-338-3p ; hsa-mir-506-3p ; hsa-mir-153-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-587
Nearest miRNA
hsa-mir-1-2/Upstream/1573041; hsa-mir-122/Downstream/2134334;
Nearest TSS
ENST00000575820/Upstream/5279; ENST00000582726/Downstream/12870;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/979033, chr18-CpG: 257/Downstream/10874
Upstream sequence
ATAAACCATCAGCACCTATGAGAACAATGAATCCACCTTCCCTGTTTTCCCAGATGCTGTACTGGCATCAACCAATATGGTACCATTACACTCAACCCTC
Downstream sequence
TCCTCTACAGGGTTGTCATCATCATGTTAAAAGCATTCAGAGGCTGAGTAACTTTGATTCTAGCCTAGTCTCAAAacacacacacacagacacacacaca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate