Basic Information
VIS ID
TVIS44028122
Fusion event
HTLV-1-DLG2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
NCBI36/hg18
Start
84423344/85034652 (Hg38)
End
84423344/85034652 (Hg38)
Orient
-
Location type
Intronic
Target gene
DLG2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10392/Upstream/3143816; hsa-let-7a-2/Downstream/1243681;
Nearest TSS
ENST00000527297/Upstream/97963; ENST00000530901/Downstream/98471;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1748159, chr11-CpG: 24/Downstream/593647
Upstream sequence
GAAGTCGAGGCTGGACAGAATTCCTTTTTTCTCCAGCATAAGAACTGAGAGTAGTTTTTCAGGAAAACTTCAGAGTCTAGGCTTGAGCAAGCAGGGAAAC
Downstream sequence
AATGAATAAAAAGACATTAATATCTTTTCTGAGCATCCTCACATTCTGTACCCTATGCTTCCCCTTTGCTGAGACTCTAGTTTCAGGGCGATCCTGTGGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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