Basic Information
VIS ID
TVIS44028126
Fusion event
HTLV-1-NUP153 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
NCBI36/hg18
Start
17788242/17680032 (Hg38)
End
17788242/17680032 (Hg38)
Orient
+
Location type
Intronic
Target gene
NUP153
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-106b-3p ; hsa-mir-330-3p ; hsa-mir-93-5p ; hsa-mir-23a-3p ; hsa-let-7b-5p ; hsa-mir-4696 ; hsa-mir-125a-3p ; hsa-mir-6888-5p ; hsa-mir-4524b-3p ; hsa-mir-552-3p ; hsa-mir-5680
Nearest miRNA
hsa-mir-3691/Upstream/1538408; hsa-mir-10398/Downstream/891752;
Nearest TSS
ENST00000381078/Upstream/79677; ENST00000606771/Downstream/26225;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/78866, chr6-CpG: 117/Downstream/26029
Upstream sequence
ccaccggccagaccactactcaaggtaatcatcgcaaccagatatgctgccttgcgtaccctaccctgcaggtgctttgcccagcccagcctgcatacct
Downstream sequence
taccccatgtcaattcctgcgctttgcctaataaaaaaaattcctactggctttttccgggaagccaggaagaggatccttgagcctcacctccactgtt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate