Basic Information
VIS ID
TVIS44028128
Fusion event
HTLV-1-ZNF710 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
NCBI36/hg18
Start
88349288/90005052 (Hg38)
End
88349288/90005052 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF710
miRNAs that regulate target gene
hsa-mir-320a ; hsa-mir-17-3p ; hsa-mir-7106-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-4722-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4784 ; hsa-mir-4459 ; hsa-mir-3150b-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-7150 ; hsa-mir-4763-3p ; hsa-mir-4736 ; hsa-mir-1207-5p ; hsa-mir-6868-5p
Nearest miRNA
hsa-mir-10393/Upstream/121022; hsa-mir-1302-10/Downstream/1703;
Nearest TSS
ENST00000557528/Upstream/2566; ENST00000558883/Downstream/62962;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2373, chr15-CpG: 65/Downstream/62471
Upstream sequence
GAGAAGCAGTTTAGTCATCGGGATTTTCTCACATCACACCATTTTTTGATCTGGAATGCTTTCTTCATACTTTGACTTGTATGTGATTTATTTAGGATTG
Downstream sequence
GTCAGGAGAGAAGAGAAGGAGTGTAAGGACCCAAGACCTGAACTGATTTCCATCTGTGGGTTAAATGTactagaacgtttgtgagggtagacgtctttgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate