Basic Information
VIS ID
TVIS44028156
Fusion event
HTLV-1-PPP1R16B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
NCBI36/hg18
Start
36966151/38904094 (Hg38)
End
36966151/38904094 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPP1R16B
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-3934-3p ; hsa-mir-6719-3p ; hsa-mir-3670 ; hsa-mir-4526 ; hsa-mir-6730-3p ; hsa-mir-3660 ; hsa-mir-3664-3p ; hsa-mir-3200-5p ; hsa-mir-6854-5p ; hsa-mir-2392 ; hsa-mir-7855-5p ; hsa-mir-6807-5p ; hsa-mir-4792 ; hsa-mir-4710 ; hsa-mir-1251-3p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-6804-3p ; hsa-mir-8069 ; hsa-mir-3065-3p ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-627-5p ; hsa-mir-6716-5p ; hsa-mir-924 ; hsa-mir-4682 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-501-5p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-3152-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-581 ; hsa-mir-511-3p ; hsa-mir-5089-5p ; hsa-mir-6506-5p ; hsa-mir-7977 ; hsa-mir-6849-3p ; hsa-mir-619-5p ; hsa-mir-1207-3p ; hsa-mir-3614-3p ; hsa-mir-34a-3p ; hsa-mir-1302 ; hsa-mir-4298 ; hsa-mir-4648 ; hsa-mir-6165 ; hsa-mir-6828-5p ; hsa-mir-873-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/387462; hsa-mir-1-1/Downstream/2264929;
Nearest TSS
ENST00000382410/Upstream/65646; ENST00000619304/Downstream/22218;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/67890, chr20-CpG: 109/Downstream/22017
Upstream sequence
GGCTCAGCAGTACCAGATATCCTCACTGCCCCTCAGGCCTGACCTGGCAGCCCAGGTGTGATAAGTGGGCTTCTCCCACCTGCTTCCTGAGCTCTCACAT
Downstream sequence
CTGTTTTATGCCCATTTCTATTACTTGGGTGCCTGCTTGGATCACCTGCTCAGCCTAGCACTCAAGAATGGGGTCAGGTAGGAAGTCTGACTATTTCTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate