Basic Information
VIS ID
TVIS44028160
Fusion event
HTLV-1-C12orf40 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
NCBI36/hg18
Start
38370435/39690366 (Hg38)
End
38370435/39690366 (Hg38)
Orient
+
Location type
Intronic
Target gene
C12orf40
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-124-3p ; hsa-mir-1-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/13816287; hsa-let-7i/Downstream/2633334;
Nearest TSS
ENST00000382841/Upstream/64148; ENST00000457989/Downstream/145394;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/246669, chr12-CpG: 108/Downstream/414794
Upstream sequence
TCAAGAGCCTTTGATGGGAGTGGGAGAGAATAGGAAAGAACAAAGTATTAGAGGAGTATAATTATTTAATTTTAAAGGTTTAGTAGAGGAATAAAGTTAA
Downstream sequence
AATACAATTGTTAACATGGGAACGTATTCACCAGAGAAGTGGAGACGTGGAAGAACAAAATTCAAGAGTGATGATGTCACACTAGGAAACCGGATCAAGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate