Basic Information
VIS ID
TVIS44028163
Fusion event
HTLV-1-MMUT integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
49531326/49455654 (Hg38)
End
49531326/49455654 (Hg38)
Orient
-
Location type
Intronic
Target gene
MMUT
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-615-3p ; hsa-mir-4776-3p ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-4753-3p ; hsa-mir-6749-3p ; hsa-mir-130b-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-8063 ; hsa-mir-483-3p ; hsa-mir-216b-5p
Nearest miRNA
hsa-mir-10398/Upstream/4257884; hsa-mir-10524/Downstream/2688695;
Nearest TSS
ENST00000381078/Upstream/1386965; ENST00000335783/Downstream/7537;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1386760, chr6-CpG: 20/Downstream/7567
Upstream sequence
gtgattgctgtactgattgaaCCACCGAATGACTTTCGACTTCCAAATTTAAATATTTCATAAACTACATTTAAGTTTTCCCATATTTTTCATACAACAT
Downstream sequence
TATTAAGAAACTGTTGTGAAACAAATGTTTCAACAGCACAGTGGATCCCAAAACATTACATTAGATAGTGCAACAGAAAAAAAAATAATAATAGATGAAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate