Basic Information
VIS ID
TVIS44028170
Fusion event
HTLV-1-VAT1L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
76463292/77871894 (Hg38)
End
76463292/77871894 (Hg38)
Orient
+
Location type
Intronic
Target gene
VAT1L
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-4503 ; hsa-mir-4662a-5p ; hsa-mir-6792-5p
Nearest miRNA
hsa-mir-1225/Upstream/1002875; hsa-mir-11401/Downstream/3513124;
Nearest TSS
ENST00000527434/Upstream/9146; ENST00000565808/Downstream/150621;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/82657, chr16-CpG: 39/Downstream/173961
Upstream sequence
CAAGAGTGTGGCACACTCTCTTTGGAAGGTCAAGAGCATCAAGCCTCAGCTCCAGTCATTTCTGGGCTGGTGTCTCCACCCACCCTGAAGGTTGAGTTGG
Downstream sequence
AGAGGTTTTGCGTACTCTTTCTTTTCATGCCCTTTTCCCAACCAAAAGACTTGAAGGTGGGGCATTTTGAAAAATGGTAATCAATCAAAGCTACCATGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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