Basic Information
VIS ID
TVIS44028184
Fusion event
HTLV-1-ART3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
77196462/76056285 (Hg38)
End
77196462/76056285 (Hg38)
Orient
-
Location type
Intronic
Target gene
ART3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-122-5p
Nearest miRNA
hsa-mir-12113/Upstream/9779357; hsa-mir-1243/Downstream/517283;
Nearest TSS
ENST00000502981/Upstream/14870; ENST00000510423/Downstream/18425;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/65186, chr4-CpG: 54/Downstream/91628
Upstream sequence
GAGTCCCAGTAACCCTAGGTGTTATCTCTCTGCTCATTCTAGGTCCCTTTCCTTCCAGAACCCTTGAAGTTTGAGTTTACATTTTTGGAAGGATGCCAGG
Downstream sequence
GATTAGCCCAGTTAGTAGATCAAGCTTCTAAGGGTTAAACTAGTGGAGGGAGACTTTTTACCTCTACCTGTGGGGTCTTCCCAAAATCTGATGAATATGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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