Basic Information
VIS ID
TVIS44028187
Fusion event
HTLV-1-MAP2K5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
NCBI36/hg18
Start
65671904/67592512 (Hg38)
End
65671904/67592512 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAP2K5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-214-3p ; hsa-mir-330-3p
Nearest miRNA
hsa-mir-10393/Upstream/1095478; hsa-mir-11181/Downstream/1209338;
Nearest TSS
ENST00000557528/Upstream/6622; ENST00000558021/Downstream/48041;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/49340, chr15-CpG: 29/Downstream/228391
Upstream sequence
acttgtcccagatcacacagctagtgaataccaggattTATTTGTACTACATATTTGCTTCCCAGGAAGCTGAATTATAACTTTTAACTGTGTAAGAGAC
Downstream sequence
CAGGACTTAAATTATCTATTTTGTCTTTTGAAGTTCTATAATCTTTATTTGCTGTGAATATTAGTGCTTAGCAGATGACATTGTCCACATGAAATTGCCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate