Basic Information
VIS ID
TVIS44028206
Fusion event
HTLV-1-NDST4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
NCBI36/hg18
Start
116083009/114942404 (Hg38)
End
116083009/114942404 (Hg38)
Orient
+
Location type
Intronic
Target gene
NDST4
miRNAs that regulate target gene
hsa-mir-526b-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-548l ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-302c-5p
Nearest miRNA
hsa-mir-12113/Upstream/285550; hsa-mir-1305/Downstream/10564855;
Nearest TSS
ENST00000502981/Upstream/320037; ENST00000604093/Downstream/171373;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/342628, chr4-CpG: 21/Downstream/1656871
Nearest cancer related gene
NDST4(TSG, No orient, 0)
Upstream sequence
tttgaaacctggagacaattgtggaaatcagataGAAGTGTCTTAATTTTTGGTGAATTTTAACCTAAGattatttaattttttaaaaaatatattatta
Downstream sequence
attttaaCTTTTAGGCATTTTCCTAGCAGAAAAGAATGATATCCTTGACACGAACATCTATAGAGGCTGAAATCTTCATCCTACTAACATTTCCTTAGTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate