Basic Information
VIS ID
TVIS44028209
Fusion event
HTLV-1-TCF12 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
55129978/57050488 (Hg38)
End
55129978/57050488 (Hg38)
Orient
+
Location type
Intronic
Target gene
TCF12
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-1224-3p ; hsa-mir-548v ; hsa-mir-33a-3p ; hsa-mir-139-5p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/1677454; hsa-mir-11181/Downstream/2120695;
Nearest TSS
ENST00000557528/Upstream/130971; ENST00000569880/Downstream/13260;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/130681, chr15-CpG: 58/Downstream/255852
Upstream sequence
GATGTCATTcctttattgtttctgataagtcttcgtatcattttgctcttatgtaatttatcttttttctctctggtgaattgaagatttctttctttgc
Downstream sequence
gtttgcactttaacatttttactattggtgcattgatgaggtttgctttgtagttctctcctacttagagactgccgagttcattggatctacagttttt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate