Basic Information
VIS ID
TVIS44028226
Fusion event
HTLV-1-ZDHHC23 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q13.31
Reference genome
NCBI36/hg18
Start
115152802/113951265 (Hg38)
End
115152802/113951265 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZDHHC23
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-337-3p ; hsa-mir-519d-5p ; hsa-mir-8063 ; hsa-mir-497-3p ; hsa-mir-4668-3p ; hsa-mir-140-3p ; hsa-mir-4724-5p ; hsa-mir-5187-3p ; hsa-mir-873-5p
Nearest miRNA
hsa-let-7g/Upstream/356323; hsa-mir-12124/Downstream/365210;
Nearest TSS
ENST00000440867/Upstream/2758; ENST00000638807/Downstream/2871;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/2722, chr3-CpG: 35/Downstream/105035
Upstream sequence
gggggtgaccctgtccccacagctccaagcaggcattgcctcagtggggtctctctgtagtggccccaccacaatgacagctccactgggcagtgcccta
Downstream sequence
gtgggggctctctgtggtggccccacccctgtggcagtcctctgcctcggtcccgaggctctccagggcatcctttgaagtctaggtggaggcagccagg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate