Basic Information
VIS ID
TVIS44028232
Fusion event
HTLV-1-SGIP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
NCBI36/hg18
Start
66928958/66690687 (Hg38)
End
66928958/66690687 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
SGIP1
miRNAs that regulate target gene
hsa-mir-510-3p ; hsa-mir-6869-5p ; hsa-mir-488-3p ; hsa-mir-526b-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548l ; hsa-mir-496 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4311 ; hsa-mir-452-3p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-3919 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4775 ; hsa-mir-4742-3p ; hsa-mir-1183
Nearest miRNA
hsa-mir-101-1/Upstream/62170; hsa-mir-11399/Downstream/1492831;
Nearest TSS
ENST00000473358/Upstream/8393; ENST00000320161/Downstream/4007;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/157310, chr1-CpG: 23/Downstream/61709
Upstream sequence
GAAATCGCCAAGGAAGGTCTTGTAATTTAGATATTATTTCTTAAAATAAAAATAGTCTCCTTTGAGGGGAAATGTTTGTTTAAATTCCAACCATGAACCA
Downstream sequence
CATCAGAAATCACAAAATTTAGAACTTGTATTTTCTTGAAGCTTTCATTTCTTCATCATTTTTGGTTGTCCTTATGTTGACAGATGATATAAACATCGGC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate