Basic Information
VIS ID
TVIS44028235
Fusion event
HTLV-1-ERO1A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
NCBI36/hg18
Start
52231106/52694638 (Hg38)
End
52231106/52694638 (Hg38)
Orient
+
Location type
Intronic
Target gene
ERO1A
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-296-3p ; hsa-mir-106b-5p ; hsa-mir-182-5p ; hsa-mir-3653-3p ; hsa-mir-203a-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4698 ; hsa-mir-4433b-3p ; hsa-mir-548p ; hsa-mir-6821-5p ; hsa-mir-7977 ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-583 ; hsa-mir-6089 ; hsa-mir-4683 ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-494-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4793-5p ; hsa-mir-6890-3p ; hsa-mir-6888-5p ; hsa-mir-6502-3p ; hsa-mir-433-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-2054 ; hsa-mir-338-5p ; hsa-mir-4458 ; hsa-mir-4462 ; hsa-mir-4500 ; hsa-mir-582-5p ; hsa-mir-6504-3p
Nearest miRNA
hsa-mir-208a/Upstream/2394692; hsa-mir-1185-1/Downstream/1253789;
Nearest TSS
ENST00000550708/Upstream/22403; ENST00000553798/Downstream/891;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/141142, chr14-CpG: 97/Downstream/482
Upstream sequence
TTTGTATAAAACGTAATTTTTATCAACAGAGTCAACCAAAAAGTGGCTTTGACAAGAGTAATCACATTGAAATACTAGATACTGAAGATAATGGAAAACT
Downstream sequence
GTAAGTTTCTCTCAATTTTTTGCTCAAGAAACCACATCTCTTACAGAAGGAAATGATCATAATCCGCTTGTAATTAAACTTGTGCACTGAAGAATAAGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate