Basic Information
VIS ID
TVIS44028238
Fusion event
HTLV-1-SUCLG2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
67649965/67516851 (Hg38)
End
67649965/67516851 (Hg38)
Orient
+
Location type
Intronic
Target gene
SUCLG2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-92a-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3679-3p ; hsa-mir-2355-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-627-3p ; hsa-mir-6734-3p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-6887-3p ; hsa-mir-3127-3p ; hsa-mir-6793-3p
Nearest miRNA
hsa-let-7g/Upstream/291324; hsa-mir-12124/Downstream/1532107;
Nearest TSS
ENST00000440867/Upstream/213972; ENST00000464420/Downstream/11371;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/518002, chr3-CpG: 45/Downstream/137353
Upstream sequence
ataagagaaatatacagatgtccaaagtgataTGGAGGAGGCAGACAGGGTCACTGTGCAACTCTGGAGCTGACTGCCAGACAGTGCAGCTAGACCACAG
Downstream sequence
TGGCTGTATGGAAAACGGGCTCTTGGTGACCACCACTGCTACAGGAGAAGCCCCTTAATAAACATCAAATGAATGGCTAATGTAGCTGGTATCCTCATTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate