Basic Information
VIS ID
TVIS44028249
Fusion event
HTLV-1-MCAT integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
NCBI36/hg18
Start
41861575/43135625 (Hg38)
End
41861575/43135625 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
MCAT
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-122-3p
Nearest miRNA
hsa-mir-1281/Upstream/1212328; hsa-let-7a-3/Downstream/2065329;
Nearest TSS
ENST00000624155/Upstream/24877; ENST00000472378/Downstream/7339;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/24021, chr22-CpG: 82/Downstream/7282
Upstream sequence
aaaaaTCAAAAGGATGAACCTAGGAGTTGTCACCTagactgggtgcacctgtctgggagcctactggggagactcctgccctgactgggaagtccttcct
Downstream sequence
gagccacttctgggcttccttccaaggctgGTAAAGGGAACGCCTAACTAGCTCCAAGACTGACCTGGGGCCACCATACCTGACCTGCCCACCATCTCAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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