Basic Information
VIS ID
TVIS44028281
Fusion event
HTLV-1-VPS41 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
38781183/38775058 (Hg38)
End
38781183/38775058 (Hg38)
Orient
+
Location type
Intronic
Target gene
VPS41
miRNAs that regulate target gene
hsa-mir-148a-3p ; hsa-let-7b-5p ; hsa-mir-197-3p ; hsa-mir-4634 ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6736-3p ; hsa-mir-4714-3p ; hsa-mir-652-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-1183/Upstream/1855626; hsa-mir-10399/Downstream/4375837;
Nearest TSS
ENST00000635602/Upstream/9305; ENST00000464276/Downstream/614;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/143497, chr7-CpG: 36/Downstream/200885
Upstream sequence
TACACAGACATACGCAGGGAAAATGGAATAATGCCCATGAAAACAGGGCAATGCAGAGTAGCATGTGACTATCCCTGCAACTATGTGAAAACATGCATGT
Downstream sequence
ACGTGAAAGGTATCACGTGGATATCTGGGGGCTATTTGGGGGATAATACTGAATGATATAAAACAAATTGTATTCAATGTCGCTAAACCACCTTTTCAGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate