Basic Information
VIS ID
TVIS44028282
Fusion event
HTLV-1-DIAPH2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q21.33
Reference genome
NCBI36/hg18
Start
96192207/97050552 (Hg38)
End
96192207/97050552 (Hg38)
Orient
-
Location type
Intronic
Target gene
DIAPH2
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-17-3p ; hsa-mir-4520-3p ; hsa-mir-4520-2-3p ; hsa-mir-20a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-4778-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-641 ; hsa-mir-3617-5p
Nearest miRNA
hsa-let-7f-2/Upstream/1987326; hsa-mir-105-1/Downstream/9589262;
Nearest TSS
ENST00000429181/Upstream/166644; ENST00000627700/Downstream/513953;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/365185, chrX-CpG: 23/Downstream/2888784
Upstream sequence
CCCAATCTATGTGAGACATCAACAACACACAAATAATAGAACCACGTTTTTTTGTTTTTTTTTTTTTTTCCTCTTCTGGAAAGAAACTACTCTTACTACT
Downstream sequence
AACATTGAAACTAGAGTCATCCTTGGACTTTATTCAAATGTGTCAGTTTTGGAAACCATACAAAGATGTTCGCTTTAGCTTAAGGGAACAGAAGAACTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate