Basic Information
VIS ID
TVIS44028300
Fusion event
HTLV-1-ARHGEF10L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
NCBI36/hg18
Start
17813682/17614600 (Hg38)
End
17813682/17614600 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ARHGEF10L
miRNAs that regulate target gene
hsa-mir-324-5p
Nearest miRNA
hsa-mir-12136/Upstream/336625; hsa-mir-101-1/Downstream/1268602;
Nearest TSS
ENST00000473358/Upstream/12429; ENST00000482359/Downstream/488;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/74552, chr1-CpG: 17/Downstream/8357
Upstream sequence
CACTTTGGGGGCTCGCAGGACAGCACCACTGATGGCTTTCTGCCAGGACAGGAACTGGATTCTGGAACAGAGGTTTCAGATCTCTGAGGGTGTGACCCCC
Downstream sequence
TCCTCCCACCCCCCAACAAGAAGAAGATGAGCGTCTATGCCATCCCTTTCGTTAGATTCTCAAAGGCCTCTATGATTACTCCCCTTGCCCAACCCCAGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate