Basic Information
VIS ID
TVIS44028304
Fusion event
HTLV-1-ELL integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
NCBI36/hg18
Start
18468805/18496995 (Hg38)
End
18468805/18496995 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ELL
miRNAs that regulate target gene
hsa-mir-769-3p ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-27a-5p ; hsa-mir-3065-5p ; hsa-mir-3131 ; hsa-mir-3153 ; hsa-mir-4270 ; hsa-mir-4327 ; hsa-mir-4417 ; hsa-mir-4441 ; hsa-mir-4668-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-5004-5p ; hsa-mir-541-3p ; hsa-mir-611 ; hsa-mir-6134 ; hsa-mir-654-5p ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-6754-5p ; hsa-mir-6785-5p ; hsa-mir-6877-5p ; hsa-mir-6883-5p ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p ; hsa-mir-7706
Nearest miRNA
hsa-mir-10395/Upstream/110361; hsa-let-7e/Downstream/938068;
Nearest TSS
ENST00000633603/Upstream/21062; ENST00000597837/Downstream/25072;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/35186, chr19-CpG: 116/Downstream/24493
Nearest cancer related gene
ELL(OG, No orient, 0)
Upstream sequence
gacagcaccaagtgctggtgaggacatggggcaacaggaacctcattcactgccggtggacatgcaaaatggtgcggcctcaacagattcctgaaaaact
Downstream sequence
aaactaacatactctcaccatccaatgcaataattgcacgccttggtatttgcccagaggcactggaaacgtgcgtccacatgaaaaatactaattacag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate