Basic Information
VIS ID
TVIS44028318
Fusion event
HTLV-1-GPC6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
NCBI36/hg18
Start
93246631/93796377 (Hg38)
End
93246631/93796377 (Hg38)
Orient
-
Location type
Intronic
Target gene
GPC6
miRNAs that regulate target gene
hsa-mir-361-5p ; hsa-mir-1279 ; hsa-mir-483-5p ; hsa-mir-32-3p ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-mir-1297/Upstream/1306157; hsa-mir-1267/Downstream/2630852;
Nearest TSS
ENST00000623511/Upstream/569060; ENST00000617456/Downstream/39767;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/567753, chr13-CpG: 59/Downstream/752929
Upstream sequence
TAACAGAGGAAAAAGAACTGTATTTTAATGAGAGTATATTTTTAAAAAGCAATTTCTTCTTTTTGCCATGCTATTTTCATTCGTAGTATTTTAGAGAGTG
Downstream sequence
GACTTTTTTTTAGCATGGAATTATGTGTATGATATTCCTTTGACCTAGCAATCACAGTACTAATAGGCTTCACATCTGTTTACTTTTAAAGAAATGTGAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate