Basic Information
VIS ID
TVIS44028321
Fusion event
HTLV-1-CACNG2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
NCBI36/hg18
Start
35401232/36675240 (Hg38)
End
35401232/36675240 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
CACNG2
miRNAs that regulate target gene
hsa-mir-205-3p ; hsa-mir-3163 ; hsa-mir-548c-3p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-2117 ; hsa-mir-26b-3p ; hsa-mir-6758-3p ; hsa-mir-6729-3p ; hsa-mir-8080
Nearest miRNA
hsa-mir-1286/Upstream/388333; hsa-let-7a-3/Downstream/1169032;
Nearest TSS
ENST00000624155/Upstream/89786; ENST00000430281/Downstream/28318;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/110233, chr22-CpG: 28/Downstream/28186
Upstream sequence
atcctcctgcctcaactttcagagtagttgggactacaggcatgtaccaccatacccagctattttttttctttttcttttttttgtagagatgcagtct
Downstream sequence
cactctgttgcccaggctggtcttgaattcttggacacaagcgatcttcccgcctcggtccccaaagtgatgggattacaggcatgagccaccatgcctg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate