Basic Information
VIS ID
TVIS44028341
Fusion event
HTLV-1-SMYD3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
NCBI36/hg18
Start
244707634/246477709 (Hg38)
End
244707634/246477709 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
SMYD3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3131454; hsa-mir-3124/Downstream/724258;
Nearest TSS
ENST00000473358/Upstream/60300; ENST00000366511/Downstream/6056;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/225442, chr1-CpG: 74/Downstream/29137
Upstream sequence
attcaattacatagttacagcaatagatattatagaaccatttttataaaagggaaaattaaagctcatggaatttacacaacttattgaatcacctagt
Downstream sequence
aactggaaaaatcagaatttgagtccagctctatcagactccaatgcccagggcttctccTGTGAGCCATATACGGCCTGTGGAGTTACTGACTGCTTAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate