Basic Information
VIS ID
TVIS44028355
Fusion event
HTLV-1-JADE1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q28.2
Reference genome
NCBI36/hg18
Start
130003231/128862626 (Hg38)
End
130003231/128862626 (Hg38)
Orient
+
Location type
Intronic
Target gene
JADE1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-145-5p ; hsa-mir-124-3p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-342-5p ; hsa-mir-324-3p ; hsa-mir-3934-3p ; hsa-mir-4427 ; hsa-mir-219b-3p ; hsa-mir-4680-3p ; hsa-mir-5010-3p ; hsa-mir-5187-3p ; hsa-mir-6854-5p ; hsa-mir-8068 ; hsa-mir-219a-2-3p
Nearest miRNA
hsa-mir-12113/Upstream/3355319; hsa-mir-1305/Downstream/14480834;
Nearest TSS
ENST00000502981/Upstream/31193; ENST00000502360/Downstream/74078;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/49796, chr4-CpG: 56/Downstream/230568
Upstream sequence
TTCTAGAGCTAGAGTGAATGAGCCCCAAGAAAATGACCCAAGGAGTTGACTCAGGATGGTTTACAGACTGATTTAGAAAACCAGAACGGATTTCATTTCT
Downstream sequence
AATGGAGGGGGCCAGAGATGGGAAAATTTCTTGTTCAGTCCGGGGAAACACACCTAGGTGCTGGTGATGGGCTTATGAAGGAAGCTAAGCACGGCTGCTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate