Basic Information
VIS ID
TVIS44028383
Fusion event
HTLV-1-DNAJC6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
NCBI36/hg18
Start
65636079/65397808 (Hg38)
End
65636079/65397808 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
DNAJC6
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-let-7c-5p ; hsa-let-7a-5p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-4260 ; hsa-mir-1227-5p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-6867-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p
Nearest miRNA
hsa-mir-101-1/Upstream/339300; hsa-mir-11399/Downstream/1230632;
Nearest TSS
ENST00000473358/Upstream/13722; ENST00000497874/Downstream/22779;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/87745, chr1-CpG: 80/Downstream/22365
Upstream sequence
AAACCGTCTAACTTCCACCTCAGTGGAATGGGTTACTGTGTAAAAATAGAAGGGATAAATAGAAAAGAAAGAATTATTATTGCTGATAATGGCATATCCT
Downstream sequence
TTTTAACTTAATGATGGGAAGGTACTAGATGACTTGGTTGGTACTAAGTAAACAAAACAAGGAAATAAAAGGTTTGGAATGCTAATCTTGATGCCTTCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate