Basic Information
VIS ID
TVIS44028394
Fusion event
HTLV-1-CDH8 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
NCBI36/hg18
Start
60601071/62009666 (Hg38)
End
60601071/62009666 (Hg38)
Orient
+
Location type
Intronic
Target gene
CDH8
miRNAs that regulate target gene
hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4469 ; hsa-mir-6832-3p ; hsa-mir-6741-3p ; hsa-mir-6867-3p ; hsa-mir-6817-3p ; hsa-mir-6845-3p ; hsa-mir-7113-3p ; hsa-mir-3667-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-642a-5p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-7110-3p ; hsa-mir-1304-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183
Nearest miRNA
hsa-mir-1225/Upstream/4237314; hsa-mir-11401/Downstream/5192655;
Nearest TSS
ENST00000527434/Upstream/90952; ENST00000415422/Downstream/11713;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2254498, chr16-CpG: 117/Downstream/25551
Upstream sequence
TTTTCATTCCACTCTTCTTTTTGGTGTTCTGGGATTCTCACTTTAAGAAGAACCTAGAAAATTGCTCAGTTTTGGCTAAAGATTCCAGTGAGCTCTCTAA
Downstream sequence
CTTTATGCTACAGCTCTGGCGTGGTTAAAAGCTCTGCCCAGCTCAGGCAAAACCAGAATCATTACACTCTGGTCACCAAGCCAGTGAGAATTTACTTCCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate