Basic Information
VIS ID
TVIS44028405
Fusion event
HTLV-1-GRID2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
NCBI36/hg18
Start
93950140/92809966 (Hg38)
End
93950140/92809966 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4E
Target gene
GRID2
miRNAs that regulate target gene
hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-448
Nearest miRNA
hsa-mir-12113/Upstream/5509383; hsa-mir-1243/Downstream/6187421;
Nearest TSS
ENST00000502981/Upstream/505309; ENST00000515744/Downstream/12983;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/504110, chr4-CpG: 112/Downstream/1018378
Upstream sequence
TATATCACCAGGTGTAGTGAAGTATAAACTTAATAATTCCTGTTAATGTCTGACCTGACACCTTGTAGATGTTCAACAAACGTTGGTCCTGTTCACTTTT
Downstream sequence
CATTTTTGAAAATATAGTATTTCATCTGATAGATACTGAGGGTTCTATTGATAATTCTTCAACTTTAAACATAATTTCAATTAGATATAAGCATAATTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate