Basic Information
VIS ID
TVIS44028430
Fusion event
HTLV-1-OPHN1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q12
Reference genome
NCBI36/hg18
Start
67424310/68287743 (Hg38)
End
67424310/68287743 (Hg38)
Orient
+
Location type
Intronic
Target gene
OPHN1
miRNAs that regulate target gene
hsa-mir-548m ; hsa-mir-3187-3p ; hsa-mir-653-3p ; hsa-mir-4529-5p ; hsa-mir-6847-3p ; hsa-mir-539-5p ; hsa-mir-3185 ; hsa-mir-3190-5p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-5680 ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-551b-5p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-7156-3p ; hsa-mir-5007-3p ; hsa-mir-1272 ; hsa-mir-8084 ; hsa-mir-3662 ; hsa-mir-8058 ; hsa-mir-4529-3p ; hsa-mir-5009-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-92a-1-5p ; hsa-mir-4515 ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-3607-3p ; hsa-mir-1208 ; hsa-mir-7844-5p ; hsa-mir-6505-5p ; hsa-mir-4789-5p ; hsa-mir-7153-3p
Nearest miRNA
hsa-let-7f-2/Upstream/2268764; hsa-mir-105-1/Downstream/1735114;
Nearest TSS
ENST00000429181/Upstream/77475; ENST00000462972/Downstream/48709;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/154662, chrX-CpG: 71/Downstream/145361
Upstream sequence
ttgcacacattgcatgattatacagacgttagttttcaaagctactatggaactgcagaaaggaataggaacatggcaaattaaaatgtcatagagctca
Downstream sequence
gtgttttctcaactattcagccatttttatttaataaacatgcactgttttgttgcaaaattttggttcgtttttggagttttaaaaaagttgattttgg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate